Nutrient blend improves function of aging brain: rat study

An antioxidant, amino acid and vitamin blend could help an aging brain and boost memory performance, according to the results of a study on rats....NT-020 is a combination of blueberry, green tea extract, carnosine and vitamin D3. Previous studies have demonstrated antioxidant and anti-inflammatory activity of the nutrient blend, which could help reduce damage in the blood, brain and other tissues in the body. In addition, in vitro and in vivo studies have also shown that the nutrient blend promotes the proliferation of stem cells"

Read more....Nutrient blend improves function of aging brain: rat study: "

EGCG, L-ascorbic acid, alpha-tocopherol, and dihydrolipoic acid on the formation of deoxyguanosine adducts derived from lipid peroxidation.

These results highlight the complexity of antioxidant mechanisms and also reveal that EGCG and DHLA are effective at suppressing lipid peroxidation-induced Acr-dG and 8-oxodG formation as well as blocking the reaction of dG with Acr

CiteULike: Effects of epigallocatechin gallate, L-ascorbic acid, alpha-tocopherol, and dihydrolipoic acid on the formation of deoxyguanosine adducts derived from lipid peroxidation.: "Nath, R. G., Wu, M. Y., Emami, A., and Chung, F.-L. L. (2010). Effects of epigallocatechin gallate, l-ascorbic acid, alpha-tocopherol, and dihydrolipoic acid on the formation of deoxyguanosine adducts derived from lipid peroxidation. Nutrition and cancer, 62(5):622-629."

Polyphenols In Red Wine And Green Tea Halt Prostate Cancer Growth

"In what could lead to a major advance in the treatment of prostate cancer, scientists now know exactly why polyphenols in red wine and green tea inhibit cancer growth. This new discovery, published online in The FASEB Journal, explains how antioxidants in red wine and green tea produce a combined effect to disrupt an important cell signaling pathway necessary for prostate cancer growth."


Polyphenols In Red Wine And Green Tea Halt Prostate Cancer Growth:

Green Tea Activates Reexpression of Glutathione Via Methylation Mechanisms.

New study demonstrates that green tea polyphenols (GTP) has dual potential to alter DNA methylation and chromatin modeling and reexpression of glutathione transferase, the 2 global epigenetic mechanisms of gene regulation and their lack of toxicity makes them excellent candidates for the chemoprevention of prostate cancer.

CiteULike: Promoter demethylation and chromatin remodeling by green tea polyphenols leads to re-expression of GSTP1 in human prostate cancer cells.: "Pandey, M., Shukla, S., and Gupta, S. (2010). Promoter demethylation and chromatin remodeling by green tea polyphenols leads to re-expression of gstp1 in human prostate cancer cells. International journal of cancer. Journal international du cancer, 126(11):2520-2533."

Drinking Green Tea May Protect Eyes

Drinking Green Tea May Protect Eyes

Green Tea Compounds May Have Therapeutic Benefits For Autoimmune Disease..

Summary: "findings suggest a potential therapeutic role for the use of EGCG to regulate inflammation and control autoimmune disease."

Reference Blog Tags: EGCG
CiteULike: Epigallocatechin-3-gallate (EGCG) attenuates inflammation in MRL/lpr mouse mesangial cells.: "Peairs, A., Dai, R., Gan, L., Shimp, S., Rylander, M. N., Li, L., and Reilly, C. M. (2010). Epigallocatechin-3-gallate (egcg) attenuates inflammation in mrl/lpr mouse mesangial cells. Cellular & molecular immunology."



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Green tea polyphenol ECGC reduces endothelin-1 expression and secretion in vascular endothelial cells: Roles for amp-activated protein kinase, akt, and foxo1.

Summary: We conclude that EGCG decreases ET-1 expression and secretion from endothelial cells, in part, via Akt- and AMPK-stimulated FOXO1 regulation of the ET-1 promoter. These findings may be relevant to beneficial cardiovascular actions of green tea.

Reiter, C. E., Kim, J.-A. A., and Quon, M. J. (2009). Green tea polyphenol epigallocatechin gallate reduces endothelin-1 expression and secretion in vascular endothelial cells: Roles for amp-activated protein kinase, akt, and foxo1. Endocrinology.

L-theanine, an amino acid in green tea, attenuated beta-amyloid-induced cognitive dysfunction and neurotoxicity: Reduction of oxidative damages and inactivation of ERK/p38 kinase and NF-kappaB pathways.

Title: L-theanine, an amino acid in green tea, attenuated beta-amyloid-induced cognitive dysfunction and neurotoxicity: Reduction of oxidative damages and inactivation of ERK/p38 kinase and NF-kappaB pathways.


Citation: Kim, T. I. I., Lee, Y. K. K., Park, S. G. G., Choi, I. S. S., Ban, J. O. O., Park, H. K. K., Nam, S.-Y. Y., Yun, Y. W. W., Han, S. B. B., Oh, K. W. W., and Hong, J. T. T. (2009). L-theanine, an amino acid in green tea, attenuated beta-amyloid-induced cognitive dysfunction and neurotoxicity: Reduction of oxidative damages and inactivation of erk/p38 kinase and nf-kappab pathways. Free radical biology & medicine.

Green tea component may help preserve stored platelets, tissues

Green tea component may help preserve stored platelets, tissues

Green Tea Protects Skin From UVB Radiation!

Definition: Dendritic cells (DC) are immune cells that take antigen and present it to other immune cells. They are present in tissue that have direct access to the external environment including the skin, nose, stomach, lungs and intestines. They possess cell-to-cell type interaction which includes communication with cytokines. Wipedia describes one example of their action includes when microbes stimulate antigens to produce IL-12 which primes the immune system for attack on antigens that DCs present. (Wipedia)

Background: Epigallcatechin gallate (EGCG) is a substance found in high amounts in green tea. It has recently been shown in studies to have benefit on the symptoms related to a mouse model of chronic fatigue. (Sachdeva)

Title: Protective effect of epigallocatechin gallate on the immune function of dendritic cells after ultraviolet b irradiation.

Summary: EGCG counteracts the inhibitory effect of UVB radiation on the immune properties of dendritic cells. It was shown in this study to down-regulate the secretion of IL-12 and up-regulates Il-10. The former Il-12 can stimulate the production of Tnf-a and IFN-gamma and is associated with autoimmune disease. The latter has an important role in modulating sickness syndrome.

Citations:

Jin, S. L., Zhou, B. R., and Luo, D. (2009). Protective effect of epigallocatechin gallate on the immune function of dendritic cells after ultraviolet b irradiation. Journal of Cosmetic Dermatology, 8(3):174-180. http://www.citeulike.org/user/HEIRS/article/5700567

Sachdeva, A. K. K., Kuhad, A., Tiwari, V., and Chopra, K. (2009). Epigallocatechin gallate ameliorates chronic fatigue syndrome in mice: Behavioral and biochemical evidence. Behavioural brain research. http://www.citeulike.org/user/HEIRS/article/5323625

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