Molecular switch Nrf2 prevents cell damage caused by UVB rays from sunlight

Molecular switch prevents cell damage caused by UVB rays from sunlight

ScienceDaily (2010-06-15) -- The protein Nrf2 plays a crucial role in tissue repair and in the protection against carcinogenesis. Cell biologists have now discovered a previously unknown role for this molecular switch, which activates numerous genes that protect cells from stress: it prevents cell damage in the skin caused by UVB rays from the sunlight. In addition, they unraveled the underlying mechanisms of action. ... > read full article

Cocaine induces oxidative damage to skin via xanthine oxidase and nitric oxide synthase

Cocaine induces oxidative damage to skin via xanthine oxidase and nitric oxide synthase

Skin photoprotection by natural polyphenols: anti-inflammatory, antioxidant and dna repair mechanisms

Summary: The laboratory studies conducted in animal models suggest that these polyphenols have the ability to protect the skin from the adverse effects of UV radiation, including the risk of skin cancers. It is suggested that polyphenols may favorably supplement sunscreens protection, and may be useful for skin diseases associated with solar UV radiation-induced inflammation, oxidative stress and DNA damage.

Nichols, J. and Katiyar, S. Skin photoprotection by natural polyphenols: anti-inflammatory, antioxidant and dna repair mechanisms. Archives of Dermatological Research. http://www.citeulike.org/user/HEIRS/article/6089276