Tuesday, October 27, 2009

Hydrogen Sulfide Increases Glutathione Production and Suppresses Oxidative Stress in Mitochondria

Title: Hydrogen sulfide increases glutathione production and suppresses oxidative stress in mitochondria.

Summary: "H2S enhances GSH by enhancing cystine/cysteine transporters and redistributes GSH to mitochondria. H2S produced in mitochondria also may directly suppress oxidative stress. It provides a new mechanism of neuroprotection from oxidative stress by H2S."

Kimura, Y., Goto, Y.-I., and Kimura, H. (2009). Hydrogen sulfide increases glutathione production and suppresses oxidative stress in mitochondria. Antioxidants & Redox Signaling, pages 091026040507095+. http://www.citeulike.org/user/HEIRS/article/6015103

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