"stimulating BDNF and reducing Aβ toxicity by natural flavonols provide a therapeutic implication for treatment of AD."
Hou, Y. et al. Anti-depressant natural flavonols modulate BDNF and beta amyloid in neurons and hippocampus of double TgAD mice. Neuropharmacology 58, 911-920 (2010). URL http://dx.doi.org/10.1016/j.neuropharm.2009.11.002.
Related:
Health and Environmental Illness Blog: Solvents, PAHs and BDNF as a Modulator of TrkB, Anxiety and Nrf2~!
Nrf2's Regulation of NRF1 and Its Influence on NMDA Subunits and Environmental Illness - see comments.
Showing posts with label tau. Show all posts
Showing posts with label tau. Show all posts
Thursday, December 9, 2010
Wednesday, September 30, 2009
Protein inhibitor helps rid brain of toxic tau protein
Protein inhibitor helps rid brain of toxic tau protein
Inhibiting the protein Hsp70 rapidly reduces brain levels of tau, a protein associated with Alzheimer's disease when it builds up abnormally inside nerve cells affecting memory, neuroscientists at the University of South Florida found. The study is reported online today in the Journal of Neuroscience.
Notes: Polymorphisms in the HSP70 have been associated with disease complications in Alzheimer's, Parkinson's disease and longevity.
Inhibiting the protein Hsp70 rapidly reduces brain levels of tau, a protein associated with Alzheimer's disease when it builds up abnormally inside nerve cells affecting memory, neuroscientists at the University of South Florida found. The study is reported online today in the Journal of Neuroscience.
Notes: Polymorphisms in the HSP70 have been associated with disease complications in Alzheimer's, Parkinson's disease and longevity.
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