Showing posts with label BPA. Show all posts
Showing posts with label BPA. Show all posts

Monday, October 25, 2010

Center to study effects of plastics chemicals on children's health

"A new research center based at the University of Illinois will investigate whether regular exposure to bisphenol A (BPA) and phthalates – chemicals widely used in plastics and other consumer products – can alter infant and adolescent development, cognition or behavior."

REad more: Center to study effects of plastics chemicals on children's health:

Thursday, August 26, 2010

Men's Health: BPA and testosterone levels

BPA and testosterone levels: "An international group of researchers led by the Peninsula Medical School and the University of Exeter have for the first time identified changes in sex hormones associated with BPA exposure in men, in a large population study. The study results are published in the latest issue of Environmental Health Perspectives."


Wednesday, June 23, 2010

BPA: Exampls of Epigenomic Disruption in Early Development

dietary BPA exposure was shown to hypomethylate both the A(vy) and the Cabp(IAP) metastable epialleles. This hypomethylating effect was counteracted with dietary supplementation of methyl donors or genistein. These results are consistent with reports of BPA and other EDCs causing epigenetic effects. Epigenotoxicity could lead to numerous developmental, metabolic, and behavioral disorders in exposed populations. The heritable nature of epigenetic changes also increases the risk for transgenerational inheritance of phenotypes. Thus, epigenotoxicity must be considered when assessing these compounds for safety.



CiteULike: Epigenomic disruption: The effects of early developmental exposures.: "Bernal, A. J. and Jirtle, R. L. (2010). Epigenomic disruption: The effects of early developmental exposures. Birth defects research. Part A, Clinical and molecular teratology."