Friday, October 16, 2009

Fats Interact With Immune Complex to Activate Inflammation -May Aggravate Autoimmune and Pathogen Infection

HEIRS Environmental Illness Research Blog: Infection/Endotoxin in Chronic Fatigue, Fibromyalgia and Multiple Chemical Sensitivity.

The interaction between toll-like receptors and fatty acids "engage" the immune complex Il-1b and its receptor to activate other inflammatory processes in the pancreas.



Böni-Schnetzler, M., Boller, S., Debray, S., Bouzakri, K., Meier, D. T., Prazak, R., Kerr-Conte, J., Pattou, F., Ehses, J. A., Schuit, F. C., and Donath, M. Y. (2009). Free fatty acids induce a proinflammatory response in islets via the abundantly expressed interleukin-1 receptor i. Endocrinology, pages en.2009-0543+. http://www.citeulike.org/user/HEIRS/article/5922922

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