Monday, October 5, 2009

Distribution of inducible nitric oxide synthase and tumor necrosis factor- in the peripheral nervous system of lewis rats during ascending paresis and spontaneous recovery from experimental autoimmune neuritis

Autoimmune Neuritis: Peripheral nerve inflammation caused by injury, poisoning, or disease, and accompanied by sensory and motor changes in the area of the affected nerve.

Title: Distribution of inducible nitric oxide synthase and tumor necrosis factor- in the peripheral nervous system of lewis rats during ascending paresis and spontaneous recovery from experimental autoimmune neuritis.

Summary: "is the first report to show iNOS- and TNF--immunoreactive cells in dorsal root ganglia during EAN, suggesting an underlying pathology for the neuropathic pain behavior in EAN. Our results suggest that the cells bearing iNOS and TNF- in the different parts of the peripheral nervous system are involved in the development of the clinical signs observed at each stage of EAN."

De La Hoza, C. L. R., Castrob, F. R., Santosc, L. M. B., and Langonec, F. (2010). Distribution of inducible nitric oxide synthase and tumor necrosis factor- in the peripheral nervous system of lewis rats during ascending paresis and spontaneous recovery from experimental autoimmune neuritis. Neuroimmunomodulation, 17(1). http://www.citeulike.org/user/HEIRS/article/5891598

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