HEIRS Environmental Illness Research Blog: PGC-1a , Cold, MCK, Myogenesis and Nrf2 and Environmental Illness?!
HEIRS Environmental Illness Research Blog: PGC-1a , Cold, MCK, Myogenesis and Nrf2 and Environmental Illness?!
Title: Possible roles of myostatin and pgc-1alpha in the increase of skeletal muscle and transformation of fiber type in cold-exposed chicks: expression of myostatin and pgc-1alpha in chicks exposed to cold.
Summary: The author noted changes in bgoth myostatin and PGC-1a from cold exposure which the former was reversed upon removal from the cold environment. However, changes in PGC-1a were not seen 24 hrs after removal. These "results indicate that myostatin and PGC-1alpha expression in the skeletal muscle rapidly change in response to acute cold, suggesting the possibility that these two genes could be involved in the increase in muscle mass and transformation of fiber type, respectively, at the initial stage of adaptation in cold-exposed chicks."
Ijiri, D., Kanai, Y., and Hirabayashi, M. (2009). Possible roles of myostatin and pgc-1alpha in the increase of skeletal muscle and transformation of fiber type in cold-exposed chicks: expression of myostatin and pgc-1alpha in chicks exposed to cold. Domestic animal endocrinology, 37(1):12-22. http://bit.ly/muscle-fibers
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