The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages

Title: The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages.

Summary: In this study, it was demonstrated that sodium hydrosulfide and a H2S donor had different effects that may help to explain how H2S can be pro- or anti-inflammatory. This study suggests that H2S activities are complex and not only dependant on concentration but also on the rate of H2S generation.

Whiteman, M., Li, L., Rose, P., Tan, C.-H. H., Parkinson, D., and Moore, P. (2009). The effect of hydrogen sulfide donors on lipopolysaccharide-induced formation of inflammatory mediators in macrophages. Antioxidants & redox signaling. http://www.citeulike.org/user/HEIRS/article/5847442