Neurotoxicity of fungal volatile organic compounds in Drosophila melanogaster

"Ingestion of the antioxidant, Vitamin E, improved the survival span and delayed the VOC-mediated changes in dopaminergic neurons indicating that the VOC-mediated toxicity was due, in part, to generation of reactive oxygen species"

Link: CiteULike: Neurotoxicity of fungal volatile organic compounds in Drosophila melanogaster:

Notes:
*******Another study demonstrates that ochratoxin, a mycotoxin formed from certain molds, inhibit glutathione production and inhibits translocation and activation of Nrf2 (Boesch-Saadatmandi).


















Boesch-Saadatmandi, C., Wagner, A. E., Graeser, A. C., Hundhausen, C., Wolffram, S., and Rimbach, G. (2009). Ochratoxin a impairs nrf2-dependent gene expression in porcine kidney tubulus cells. Journal of animal physiology and animal nutrition, 93(5):547-554. http://www.citeulike.org/user/HEIRS/article/4365611

Inamdar, A. A., Masurekar, P., and Bennett, J. W. (2010). Neurotoxicity of fungal volatile organic compounds in drosophila melanogaster. Toxicol. Sci., pages kfq222+. http://www.citeulike.org/user/HEIRS/article/7529557

The biocontaminants and complexity of damp indoor spaces: more than what meets the eye.

Title: Biocontaminants and complexity of damp indoor spaces: more than what meets the eye.

Summary: The synergism between mycotoxins and endotoxins from gram negative and some gram positive bacteria are discussed. As well as, where mycotoxins and the type can lerk.

Thrasher, J. D. and Crawley, S. (2009). The biocontaminants and complexity of damp indoor spaces: more than what meets the eye. Toxicology and industrial health. http://www.citeulike.org/group/7269/article/5908276