Prenatal Polycyclic Aromatic Hydrocarbon Exposure Leads to Behavioral Deficits and Downregulation of Receptor Tyrosine Kinase, MET — Toxicol Sci

"common pollutants, such as the polycyclic aromatic hydrocarbon benzo(a)pyrene, can have a direct, negative impact on the regulated developmental expression of an autism risk gene with associated negative behavioral learning and memory outcomes."

Read more: Prenatal Polycyclic Aromatic Hydrocarbon Exposure Leads to Behavioral Deficits and Downregulation of Receptor Tyrosine Kinase, MET — Toxicol Sci:

Scientists find link in humans between nerve cell production and memory

"Production of new nerve cells in the human brain is linked to learning and memory, according to a new study from the University of Florida."

Read more:Scientists find link in humans between nerve cell producti... ( Production of new nerve cells in the...):

Dr. Francis Lee on the BDNF molecule and anxiety disorder research- Watch!

"BDNF stands for brain derived neurotrophic factor. This molecule, found in the brain's fear hub could have a significant impact on the study of anxiety disorders including Post Traumatic Stress Disorder. Dr. Francis Lee of Weill-Cornell Medical College is a leading BDNF investigator and was a recent guest lecturer at the National Institute of Mental Health." Read more or watch...

NIMH · Speaking of Science - Dr. Francis Lee on the BDNF molecule and anxiety disorder research:






Read:
Article: Inducing a safety memory in the brain

For further reading: HEIRS Blog Tags: BDNF



****HEIRS Library: BDNF






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Postive Effects of Exercise on Memory from BDNF Resistance to Corticosterone.

Corticosterone is a main glucocorticoid  involved in regulation of fuel, immune reactions, and stress responses. (Corticosterone: Wipedia)

"This study suggests that the resistance of the hippocampal BDNF expression to suppression by corticosterone, as seen after water maze training, may contribute to an optimal memory performance." (Schaff)

Comment: It has been suggested that exercise exerts its influence by increasing a number of different hormones and cellular activators including BDNF and enhances memory and learning by activating the antioxidant system. (Ayoub) BDNF has been implicated as a factor in a number of mood disorders and altered levels in conditions including PTSD, fibromyagia and CFS and proteins such as GSK-3b may alter BDNF's downstream regulators. (Mai)
For more: HEIRS Library Tag: BDNF  
Related Blogs: BDNF 

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CiteULike: Corticosterone effects on BDNF expression in the hippocampus. Implications for memory formation.: "suggest that the resistance of the hippocampal BDNF expression to suppression by corticosterone, as seen after water maze training, may contribute to an optimal memory performance."
Schaaf, M. J., De Kloet, E. R., and Vreugdenhil, E. (2000). Corticosterone effects on bdnf expression in the hippocampus. implications for memory formation. Stress (Amsterdam, Netherlands), 3(3):201-208. http://www.citeulike.org/user/HEIRS/article/7224956




Other Sources:
Ayoub, R. S. (2009). Effect of exercise on spatial learning and memory in male diabetic rats. 18(3). http://www.citeulike.org/user/HEIRS/article/7224997
Mai, L., Jope, R. S., and Li, X. (2002). Bdnf-mediated signal transduction is modulated by gsk3β and mood stabilizing agents. Journal of Neurochemistry, 82(1):75-83. http://www.citeulike.org/user/HEIRS/article/6621876















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