Background: A past study has shown that H2S, cinnaldehyde and isothiocyanates can activate TRPA1 channels in the urinary bladder altering function. (Gratske) This would suggest that the health effects of Chinese drywall are at least in part, mediated by the effect of both formaldehyde and H2S on TRPA1 channels.
The Consumer Product Safety Commission has some unsettling advice for people who live in homes built with Chinese-made drywall: "Spend as much time outdoors in fresh air as possible. According to the article.........."While hydrogen sulfide and formaldehyde were found at levels lower than the amount considered to be irritants, officials speculated that the two could be combining to produce higher levels of irritation than either would alone......Representatives of the formaldehyde industry said it is irresponsible to speculate that the two substances, at the levels found in the CPSC study, can act in a synergistic manner."
Read complete article.
Related article: Research Reveals Exactly How Coughing Is Triggered By Environmental Irritants
Transient receptor potential A1 (TRPA1) ion channel activity in the human urethra - evidence for a functional role of TRPA1 in the outflow region.
http://www.icsoffice.org/ASPNET_Membership/Membership/Abstracts/Publish/46/000027.pdf
Showing posts with label irritants. Show all posts
Showing posts with label irritants. Show all posts
Tuesday, November 24, 2009
Monday, November 23, 2009
Research reveals exactly how coughing is triggered by environmental irritants
Background: TRPA1 is sensitized by cytokines such as MCP-1 produces as part of the immune stress response.
Scientists have revealed how environmental irritants such as air pollution and cigarette smoke cause people to cough, in research published today in the American Journal of Respiratory and Critical Care Medicine. The authors of the study, from Imperial College London and the University of Hull, have identified the reaction inside the lungs that can trigger coughing when a person is exposed to particular irritants in the air. They suggest that their findings may ultimately lead to the development of new treatments for chronic coughing... Read more...
HEIRS Health & Home
heirshealth@gmail.com
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Scientists have revealed how environmental irritants such as air pollution and cigarette smoke cause people to cough, in research published today in the American Journal of Respiratory and Critical Care Medicine. The authors of the study, from Imperial College London and the University of Hull, have identified the reaction inside the lungs that can trigger coughing when a person is exposed to particular irritants in the air. They suggest that their findings may ultimately lead to the development of new treatments for chronic coughing... Read more...
HEIRS Health & Home
heirshealth@gmail.com
***HEIRS Store***
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