Showing posts with label folates. Show all posts
Showing posts with label folates. Show all posts

Thursday, June 24, 2010

Not enough folate may quicken hearing loss: Study

"Low blood levels of folate are associated with a 35 per cent increased risk of hearing loss, says a new study from Australia that strengthens the link between B vitamins and hearing."


Not enough folate may quicken hearing loss: Study:

Wednesday, June 16, 2010

Dioxin downregulation folate carrier transport through the AhR.

deregulation of this essential transport pathway represents a novel regulatory mechanism how dioxins display their toxic effects through the Ah receptor
CiteULike: Dioxin mediates downregulation of the reduced folate carrier transport activity via the arylhydrocarbon receptor signalling pathway.: "Halwachs, S., Lakoma, C., Gebhardt, R., Schäfer, I., Seibel, P., and Honscha, W. (2010). Dioxin mediates downregulation of the reduced folate carrier transport activity via the arylhydrocarbon receptor signalling pathway. Toxicology and applied pharmacology, 246(1-2):100-106."

Tuesday, May 25, 2010

Folates Benefits on CNS Injury Mediates Through Methylation!

"New study implicates an epigenetic mechanism in CNS repair. Folic acid and possibly other nontoxic dietary methyl donors may therefore be useful in clinical interventions to promote brain and spinal cord healing. If indeed the benefit of folate is mediated by epigenetic mechanisms that promote endogenous axonal regeneration, this provides possible avenues for new pharmacologic approaches to treating CNS injuries."



CiteULike: Folate regulation of axonal regeneration in the rodent central nervous system through DNA methylation.: "Iskandar, B. J., Rizk, E., Meier, B., Hariharan, N., Bottiglieri, T., Finnell, R. H., Jarrard, D. F., Banerjee, R. V., Skene, P. H., Nelson, A., Patel, N., Gherasim, C., Simon, K., Cook, T. D., and Hogan, K. J. (2010). Folate regulation of axonal regeneration in the rodent central nervous system through dna methylation. The Journal of clinical investigation, 120(5):1603-1616."