Wednesday, June 16, 2010

Dioxin downregulation folate carrier transport through the AhR.

deregulation of this essential transport pathway represents a novel regulatory mechanism how dioxins display their toxic effects through the Ah receptor
CiteULike: Dioxin mediates downregulation of the reduced folate carrier transport activity via the arylhydrocarbon receptor signalling pathway.: "Halwachs, S., Lakoma, C., Gebhardt, R., Schäfer, I., Seibel, P., and Honscha, W. (2010). Dioxin mediates downregulation of the reduced folate carrier transport activity via the arylhydrocarbon receptor signalling pathway. Toxicology and applied pharmacology, 246(1-2):100-106."

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