"basal oxygen consumption of colonocytes was similar in the NP and HP groups, but ammonia was found to provoke a dose-dependent decrease of oxygen consumption in the isolated absorbing colonocytes. The activity of glutamine synthetase (which condenses ammonia and glutamate) was found to be much higher in colonocytes than in small intestine enterocytes and was 1.6-fold higher (p=0.0304) in colonocytes isolated from HP animals than NP. Glutaminase activity remained unchanged."
Read more: CiteULike: Colon luminal content and epithelial cell morphology are markedly modified in rats fed with a high protein diet.:
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