Glucuronidation: phase II detoxification pathway occurring in the liver in which glucuronic acid is conjugated with toxins. Effectively detoxifies the majority of commonly prescribed drugs. (Source Link: glucuronidation )
"UGT1A genes are induced in vitro and in vivo by coffee, independent of caffeine content, cafestol, or kahweol. Coffee upregulates glucuronidation via AhR signaling and Nrf2 binding to the ARE/XRE. Glucuronidation could mediate the protective and antioxidant effects of coffee."
CiteULike: Coffee induces expression of glucuronosyltransferases via the aryl hydrocarbon receptor and Nrf2 in liver and stomach.:
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