Wednesday, June 23, 2010

Tumor Necrosis Factor-Induced Neutrophil Adhesion Occurs Through SphK-1 Activation of Integrin

"TNFalpha activated endothelial cells being sphingosine kinase-1, alpha5beta1, and angiopoietin-2 dependent. Moreover, this work supports the notion that sphingosine kinase-1 may be the single target required for an effective broad spectrum approach to combat inflammation and immune disorders."


Tumor Necrosis Factor-Induced Neutrophil Adhesion ... [Am J Pathol. 2010] - PubMed result:

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