Tuesday, March 16, 2010

Memory T Cells and IL-10 In Autoreactive Suppression.

We propose the novel concept that a population of memory T cells, which is fully equipped to participate in secondary immune responses upon recognition of a relevant recall antigen, contributes to the maintenance of tolerance under steady-state conditions. 10.1084/jem.20091021




CiteULike: CCR6 is expressed on an IL-10-producing, autoreactive memory T cell population with context-dependent regulatory function: "Rivino, L., Gruarin, P., Haringer, B., Steinfelder, S., Lozza, L., Steckel, B., Weick, A., Sugliano, E., Jarrossay, D., Kuhl, A. A., Loddenkemper, C., Abrignani, S., Sallusto, F., Lanzavecchia, A., and Geginat, J. (2010). Ccr6 is expressed on an il-10-producing, autoreactive memory t cell population with context-dependent regulatory function. J. Exp. Med., 207(3):565-577."

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