Keap1-Nrf2 activation in the presence and absence of DJ-1. Li Gan. 2010; European Journal of Neuroscience - Wiley InterScience: "In addition, overexpression of Nrf2 with adenovirus preferentially in astrocytes from DJ-1-KO mice enhanced survival of neurons under oxidative insults. These findings indicate that activation of the Nrf2–ARE pathway is independent of DJ-1, and Nrf2 activation is a potential therapeutic target to prevent neurodegeneration in sporadic and DJ-1 familial Parkinson's disease."
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