Apocynin attenuate spatial learning deficits and oxidative responses to intermittent hypoxia

Apocynin attenuate spatial learning deficits and oxidative responses to intermittent hypoxia: "These results indicate that apocynin attenuates LTIH-induced spatial learning deficits and mitigates LTIH-induced oxidative stress through multiple beneficial effects on oxidant pathways. NADPH oxidase up-expression is closely associated with oxidative processes in LTIH rats, and inhibition of NADPH oxidase activity may hopefully serve as a useful strategy for cognitive function impairment from chronic intermittent hypoxia."