Summary: Resveratrol counteracted LPS effect by decreasing CD14 and IRAK1 expression but unexpectedly increased the p38 MAPK protein phosphorylation. Altogether, our data highlighted the functionality of the TLR4-Myd88 signaling pathway in LPS prooxidant effect using non myeloid cells.
Sebai, H., Ristorcelli, E., Sbarra, V., Hovsepian, S., Fayat, G., Aouani, E., and Lombardo, D. (2009). Protective effect of resveratrol against lps-induced extracellular lipoperoxidation in ar42j cells partly via a myd88-dependent signaling pathway. Archives of biochemistry and biophysics. http://www.citeulike.org/user/HEIRS/article/6457832
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