Expression of TLR4 and CD14 in the Central Nervous System (CNS) in a MPTP Mouse Model of Parkinson's-Like Disease

Title: Expression of tlr4 and cd14 in the central nervous system (cns) in a mptp mouse model of parkinson's-like disease.

Summary: Results demonstrated an augmented expression of both CD14 and TLR4 in the substantia nigra of mice treated with MPTP in comparison to untreated animals, suggesting that the endotoxin receptors are over expressed in different manner in specific areas of the CNS during Parkinson's-like disease.

Panaro‌, M. A., Lofrumento, D. D., Saponaro‌, C., De Nuccio, F., Cianciulli, A., Mitolo, V., and Nicolardi‌, G. (2008). Expression of tlr4 and cd14 in the central nervous system (cns) in a mptp mouse model of parkinson's-like disease. Immunopharmacology and Immunotoxicology, 30(4):729-740. http://www.citeulike.org/user/HEIRS/article/6334780