HEIRS Environmental Illness Research Blog: HEIRS Environmental Illness Research Blog: Sickness Syndrome, CFS, Fibromyalgia, IL-10 and HO-1
Sasaki et al: Induction of the xCT transporter by electrophiles (in this case, dimethyl maleate which is used to manufacturing of plastics, pigments, paints, adhesives, etc) is through actions of the Nrf2. It also regulates detox of arsenic, cadmium and hydroquinone.
Sasaki, H., Sato, H., Kuriyama-Matsumura, K., Sato, K., Maebara, K., Wang, H., Tamba, M., Itoh, K., Yamamoto, M., and Bannai, S. (2002). Electrophile response element-mediated induction of the cystine/glutamate exchange transporter gene expression. J. Biol. Chem., pages M208704200+. http://www.citeulike.org/group/7167/article/4302335
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