A new study has reported that Astragalus may prove an effective therapy against intestinal inflammation caused by LPS endotoxin. The study demonstrated that Tnf-a and Il-8 is significantly higher in LPS-induced damage in intestinal epithelial cells. Treatment with Astragalus mongholicus polysaccharide (APS) significantly abrogated LPS-endotoxin expression of Tnf-a and Il-8 and suggested this is achieved by blocking the P38Mapk pathway.
Yuan, Y., Sun, M., and Li, K.-S. S. (2009). Astragalus mongholicus polysaccharide inhibits lipopolysaccharide-induced production of tnf-alpha and interleukin-8. World journal of gastroenterology : WJG, 15(29):3676-3680. http://www.citeulike.org/user/HEIRS/article/5390452
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