Abstracts on Pneumococcal Infection (& other bacteria) Added to the Library

Villena, J., Barbieri, N., Salva, S., Herrera, M., and Alvarez, S. (2009). Enhanced immune response to pneumococcal infection in malnourished mice nasally treated with heat-killed lactobacillus casei. Microbiology and immunology, 53(11):636-646.
http://www.citeulike.org/user/HEIRS/article/6467481

Saini, A., Harjai, K., Mohan, H., Punia, R. P. S. P., and Chhibber, S. (2009). Long-term flaxseed oil supplementation diet protects balb/c mice against streptococcus pneumoniae infection. Medical microbiology and immunology.
http://www.citeulike.org/user/HEIRS/article/6226768

Wenger, J. D., Zulz, T., Bruden, D., Singleton, R., Bruce, M. G., Bulkow, L., Parks, D., Rudolph, K., Hurlburt, D., Ritter, T., Klejka, J., and Hennessy, T. (2009). Invasive pneumococcal disease in alaskan children: Impact of the seven-valent pneumococcal conjugate vaccine and the role of water supply. The Pediatric infectious disease journal.
http://www.citeulike.org/user/HEIRS/article/6467478

Lacapa, R., Bliss, S. J., Larzelere-Hinton, F., Eagle, K. J., McGinty, D. J., Parkinson, A. J., Santosham, M., Craig, M. J., and O'Brien, K. L. (2008). Changing epidemiology of invasive pneumococcal disease among white mountain apache persons in the era of the pneumococcal conjugate vaccine. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 47(4):476-484.
http://www.citeulike.org/user/HEIRS/article/6467475

Phipps, J. C., Aronoff, D. M., Curtis, J. L., Goel, D., O'Brien, E., and Mancuso, P. (2009). Cigarette smoke-exposure impairs pulmonary bacterial clearance and alveolar macrophage complement-mediated phagocytosis of s. pneumoniae. Infection and immunity.
http://www.citeulike.org/user/HEIRS/article/6467469

Maddox, J. F., Amuzie, C. J., Li, M., Newport, S. W., Sparkenbaugh, E., Cuff, C. F., Pestka, J. J., Cantor, G. H., Roth, R. A., and Ganey, P. E. (2010). Bacterial- and viral-induced inflammation increases sensitivity to acetaminophen hepatotoxicity. Journal of toxicology and environmental health. Part A, 73(1):58-73.
http://www.citeulike.org/user/HEIRS/article/6465503

Saw, C. L. L. L., Huang, Y., and Kong, A.-N. N. (2010). Synergistic anti-inflammatory effects of low doses of curcumin in combination with polyunsaturated fatty acids: docosahexaenoic acid or eicosapentaenoic acid. Biochemical pharmacology, 79(3):421-430.http://www.citeulike.org/user/HEIRS/article/5765677

Sebai, H., Ben-Attia, M., Sani, M., Aouani, E., and Ghanem-Boughanmi, N. (2009). Protective effect of resveratrol in endotoxemia-induced acute phase response in rats. Archives of toxicology, 83(4):335-340.
http://www.citeulike.org/user/HEIRS/article/6463192

Aran, A., Lin, L., Nevsimalova, S., Plazzi, G., Hong, S. C. C., Weiner, K., Zeitzer, J., and Mignot, E. (2009). Elevated anti-streptococcal antibodies in patients with recent narcolepsy onset. Sleep, 32(8):979-983.
http://www.citeulike.org/user/HEIRS/article/6463176

Gaykema, R. P. and Goehler, L. E. (2009). Lipopolysaccharide challenge-induced suppression of fos in hypothalamic orexin neurons: their potential role in sickness behavior. Brain, behavior, and immunity, 23(7):926-930.
http://www.citeulike.org/user/HEIRS/article/4967509

Tokairin, Y., Shibata, Y., Sata, M., Abe, S., Takabatake, N., Igarashi, A., Ishikawa, T., Inoue, S., and Kubota, I. (2008). Enhanced immediate inflammatory response to streptococcus pneumoniae in the lungs of mice with pulmonary emphysema. Respirology (Carlton, Vic.), 13(3):324-332.
http://www.citeulike.org/user/HEIRS/article/2651950

Ozlu, T., Celik, I., Oztuna, F., Bulbul, Y., and Ozsu, S. (2008). Streptococcus pneumoniae adherence in rats under different degrees and durations of cigarette smoke. Respiration; international review of thoracic diseases, 75(3):339-344.
http://www.citeulike.org/user/HEIRS/article/6462971

Garbin, U., Fratta Pasini, A., Stranieri, C., Cominacini, M., Pasini, A., Manfro, S., Lugoboni, F., Mozzini, C., Guidi, G., Faccini, G., and Cominacini, L. (2009). Cigarette smoking blocks the protective expression of nrf2/are pathway in peripheral mononuclear cells of young heavy smokers favouring inflammation. PLoS ONE, 4(12):e8225+. http://www.citeulike.org/user/HEIRS/article/6467492

Columbia University's Mailman School of Public Health (2009, December 31). Severity of H1N1 influenza linked to presence of Streptococcus pneumoniae. ScienceDaily. Retrieved January 1, 2010, from http://www.sciencedaily.com/releases/2009/12/091230201419.htm

Cigarette Smoking and Invasive Pneumococcal Disease - Implications for Severity of H1N1

Cigarette smoking is the strongest risk factor for pneumococcal disease among immunocompetant non-elderly people. (Nuorti) As we have noted, cigarette also disrupts the major antioxidant system Nrf2. A recent report has shown that pneumococcal disease makes complications from H1N1 much more severe. Because of the relationship of Nrf2 and its important influence on modulation of inflammatory processes. It is worth suggesting that the dysruption of Nrf2 may contribute to H1N1 infection complications and because there have been polymorphs in Nrf2 identified - these polymorphs may make a person either more at risk or less at risk for complications related to H1N1. The implications of this includes that unless a person understands these risk factors related to their own genetic makeup it is advisable to take a physician's advice that is based on recent knowledge and understanding instead of those who claim to be "experts" in environmental disease.


CiteULike: Cigarette Smoking and Invasive Pneumococcal Disease: "Nuorti, J. P., Butler, J. C., Farley, M. M., Harrison, L. H., McGeer, A., Kolczak, M. S., Breiman, R. F., and Team, T. A. B. C. S. (2000). Cigarette smoking and invasive pneumococcal disease. N Engl J Med, 342(10):681-689."


Tokairin, Y., Shibata, Y., Sata, M., Abe, S., Takabatake, N., Igarashi, A., Ishikawa, T., Inoue, S., and Kubota, I. (2008). Enhanced immediate inflammatory response to streptococcus pneumoniae in the lungs of mice with pulmonary emphysema. Respirology (Carlton, Vic.), 13(3):324-332. http://www.citeulike.org/user/HEIRS/article/2651950

Nuorti, J. P., Butler, J. C., Farley, M. M., Harrison, L. H., McGeer, A., Kolczak, M. S., Breiman, R. F., and Team, T. A. B. C. S. (2000). Cigarette smoking and invasive pneumococcal disease. N Engl J Med, 342(10):681-689. http://www.citeulike.org/user/HEIRS/article/6462894

Reddy, N. M., Suryanarayana, V., Kalvakolanu, D. V., Yamamoto, M., Kensler, T. W., Hassoun, P. M., Kleeberger, S. R., and Reddy, S. P. (2009). Innate immunity against bacterial infection following hyperoxia exposure is impaired in nrf2-deficient mice. J Immunol, 183(7):4601-4608.

Severity of H1N1 influenza linked to presence of Streptococcus pneumoniae. EurekAlert. December 31, 2009. http://www.eurekalert.org/pub_releases/2009-12/cums-soh123009.php