The severity of liver and gut microbiota alterations induced by I/R was even greater in rats with liver inflammation and steatosis, i.e., MCD-fed animals. LP-F19 supplementation significantly reduced the harmful effects of I/R on the liver and on gut microbiota in both groups of rats, although the effect was slightly less in MCD-fed animals. In conclusion, LP-F19 supplementation, by restoring gut microbiota, attenuated I/R-related liver injury, particularly in the absence of steatosis.
CiteULike: PROTECTIVE EFFECTS OF LACTOBACILLUS PARACASEI F19 IN A RAT MODEL OF OXIDATIVE AND METABOLIC HEPATIC INJURY.: "Nardone, G., Compare, D., Liguori, E., Di Mauro, V., Rocco, A., Barone, M., Napoli, A., Lapi, D., Iovene, M. R. R., and Colantuoni, A. (2010). Protective effects of lactobacillus paracasei f19 in a rat model of oxidative and metabolic hepatic injury. American journal of physiology. Gastrointestinal and liver physiology."
For further reading: Library: Probiotics and Prebiotics
HEIRS Research Blog: Probiotics
