Ghrelin Provides Positive Metabolic Effects Through Nitric Oxide Regulation.

"ghrelin plays a significant role in the regulation of glucose homeostasis, lipid profiles and body composition. Importantly, ghrelin has antinflammatory and antiapoptotic effects both in vivo and in vitro."

Note: Some of its action is achieved through signalling via NO/cGMP. Excess production of ammonia such as those from bacteria may influence the regulation of this protein.

CiteULike: Cardiovascular and Metabolic Effects of Ghrelin.: "Tesauro, M., Schinzari, F., Caramanti, M., Lauro, R., and Cardillo, C. (2010). Cardiovascular and metabolic effects of ghrelin. Current diabetes reviews."