PPAR-gamma Protects Against Pathogenic Strains of Influenza~!

Considering the evidence from this study and others, chemical pollutants, drugs and environmental conditions that positively or negative regulate PPAR-gamma should be an important consideration when evaluating an individual for different environmental illnesses and alterations in cellular homeostasis. In addition, the recent studies that PPAR-gamma is regulated by Nrf2 also puts more emphasis as an important target for environmentally-induced disease.

 

"preliminary evidence that two classes of drugs, peroxisome proliferator-activated receptor-gamma agonists and AMP-activated protein kinase agonists, provide protection in mice infected with highly pathogenic and pandemic strains of influenza virus."

Read more: CiteULike: Moseley, C. E., Webster, R. G., and Aldridge, J. R. (2010). Peroxisome proliferator-activated receptor and amp-activated protein kinase agonists protect against lethal influenza virus challenge in mice. Influenza and other respiratory viruses, 4(5):307-311. http://www.citeulike.org/user/HEIRS/article/7679239


For Further Reading: Nrf2, PPAR-gamma