Sunday, August 8, 2010

AKT/GSK-3beta/beta-catenin signalling within hippocampus and amygdala reflects genetically determined differences in posttraumatic stress disorder like symptoms.

"Taken together our study identifies lasting changes in the AKT/GSK-3beta/beta-catenin cascade within the hippocampus and amygdala as molecular correlates of genetically determined differences in the severity of PTSD-like symptoms."

CiteULike: AKT/GSK-3beta/beta-catenin signalling within hippocampus and amygdala reflects genetically determined differences in posttraumatic stress disorder like symptoms.:

Supplemental: Resveratrols, a compound found in wine and grapes exert their protective effects against neuronal damage and death are mediated throught this same pathway.

Fukui, M., Choi, H. J. J., and Zhu, B. T. T. (2010). Mechanism for the protective effect of resveratrol against oxidative stress-induced neuronal death. Free radical biology & medicine, 49(5):800-813. http://www.citeulike.org/user/HEIRS/article/7301406
Xi, J., Wang, H., Mueller, R. A., Norfleet, E. A., and Xu, Z. (2009). Mechanism for resveratrol-induced cardioprotection against reperfusion injury involves glycogen synthase kinase 3beta and mitochondrial permeability transition pore. European journal of pharmacology, 604(1-3):111-116. http://www.citeulike.org/user/HEIRS/article/7588469

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