This is the first to show a substantial corroboration of the biological significance of cellular 8-nitro-cGMP formation and potential roles of 8-nitro-cGMP in the Nrf2-dependent antioxidant response.
CiteULike: The critical role of nitric oxide signaling, via protein S-guanylation and nitrated cyclic GMP, in the antioxidant adaptive response.: "Fujii, S., Sawa, T., Ihara, H., Tong, K. I., Ida, T., Okamoto, T., Ahtesham, A. K. K., Ishima, Y., Motohashi, H., Yamamoto, M., and Akaike, T. (2010). The critical role of nitric oxide signaling, via protein s-guanylation and nitrated cyclic gmp, in the antioxidant adaptive response. The Journal of biological chemistry."
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