Sunday, April 4, 2010

Toxic Chemicals In Upholstery May Increase Susceptibility to Infection.

Background: I have suggested that PFOA plays a part in MCS by altering the genes in the methionine cycle that could influence ammonia detoxification. Other new studies demonstrate that effects of methionine metabolism may be exacerbated by deficiencies in the Nrf2 which is neuroprotective through numerous mechanisms including regulating transferases, ornithine proteins and modulating cobalamin upregulation.

Findings of a new study on the toxicity of PFOA chemicals in carpets, upholstery, etc. may alter the function of immune cells called lysozymes. Wipedia explains these cells are responsible for providing protection from damage from invading bacteria and are found in secretions from membranes such as tears and mucus. Infants lacking these enzymes have elevations in diarrheal disease; potentially because they fight against infection of bacteria such as Salmonella, E. coli and Pseudomonas.

Question: Why on earth do they still use this stuff?

Further Reading: PFOA alters liver gene expression.(CHEMICAL EXPOSURES): An article from: Environmental Health Perspectives

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Wu, L.-L. L., Chen, L., Song, C., Liu, X.-W. W., Deng, H.-P. P., Gao, N.-Y. Y., and Gao, H.-W. W. (2010). Potential enzyme toxicity of perfluorooctanoic acid. Amino acids, 38(1):113-120. http://www.citeulike.org/user/HEIRS/article/3746495

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