"modest (~25%) upregulation of PGC-1alpha, within physiologic limits, does improve mitochondrial biogenesis, fatty acid oxidation and insulin sensitivity in healthy and insulin resistant skeletal muscle."
PGC-1{alpha} REGULATION BY EXERCISE TRAINING AND AND ITS INFLUENCES ON MUSCLE FUNCTION AND INSULIN SENSITIVITY [Am J Physiol Endocrinol Metab. 2010] - PubMed result:
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