Monday, March 15, 2010

Skeletal Muscle Insulin Resistance in Endocrine Disease

Skeletal Muscle Insulin Resistance in Endocrine Disease: "The principal mechanisms involved in muscle IR in the endocrine diseases reviewed herein include abnormal phosphorylation of insulin signaling proteins, altered muscle fiber composition, reduced transcapillary insulin delivery, decreased glycogen synthesis, and impaired mitochondrial oxidative metabolism."

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