Differences in Gene and Cell Behavior in Radical-Induced Oxidative Stress

This study offers a novel and detailed insight in the similarities and differences of the time-dependent oxidative stress responses induced by the oxidants H2O2 and menadione and show that these can be discriminated regarding their modulation of particular colon carcinogenesis-related mechanisms.

CiteULike: Global Gene Expression Analysis Reveals Differences in Cellular Responses to Hydroxyl- and Superoxide Anion Radical-Induced Oxidative Stress in Caco-2 Cells: "Briede, J. J., van Delft, J. M. H., de Kok, T. M. C. M., van Herwijnen, M. H. M., Maas, L. M., Gottschalk, R. W. H., and Kleinjans, J. C. S. (2010). Global gene expression analysis reveals differences in cellular responses to hydroxyl- and superoxide anion radical-induced oxidative stress in caco-2 cells. Toxicol. Sci., 114(2):193-203."