Myelin Basic Protein Priming Reduces the Expression of Foxp3 in T Cells via Nitric Oxide.

In a preceding blog, we discussed how FOXP3 in important for autoimmune suppressing T cells. We also described how a recent study suggests that the loss of Tregs may be a contributing factor in chemical sensitivity and environmental illnesses from exposures to air contaminants. Here we see that NO is a factor in the altered expression in FOX3P Tregs.


CiteULike: Myelin Basic Protein Priming Reduces the Expression of Foxp3 in T Cells via Nitric Oxide.: "Brahmachari, S. and Pahan, K. (2010). Myelin basic protein priming reduces the expression of foxp3 in t cells via nitric oxide. Journal of immunology (Baltimore, Md. : 1950)."