Chemical, caffeic acid, in the substance that honey bees collect called propolis has been shown to have health benefits by inhibiting an inflammatory pathway that initiates inflammatory immune complexes. Generally, propolis has been used in traditional or folk medicine for a variety of ailments. Caffeic acid, according to Wipedia, it a exceptional antioxidant but as another source says quantities of compounds in propolis may differ according to time of year, one must take care when "extrapolating" health benefits.
CiteULike: Caffeic acid phenethyl ester inhibits nuclear factor-κB and protein kinase B signalling pathways and induces caspase-3 expression in primary human CD4<sup>+</sup> T cells: "Wang, L. C., Chu, K. H., Liang, Y. C., Lin, Y. L., and Chiang, B. L. (2010). Caffeic acid phenethyl ester inhibits nuclear factor-κb and protein kinase b signalling pathways and induces caspase-3 expression in primary human cd4+ t cells. Clinical & Experimental Immunology, 9999(9999)."
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