Microbial infections in eight genomic subtypes of Chronic Fatigue Syndrome / Myalgic Encephalomyelitis (CFS/ME)

Microbial infections in eight genomic subtypes of chronic fatigue syndrome / myalgic encephalomyelitis (cfs/me).

Summary: Clustering of combined gene data in CFS/ME patients for this and our previous study (n=117 CFS/ME patients) revealed genomic subtypes with distinct differences in SF-36 scores, clinical phenotypes, severity and geographical distribution. Antibody testing for Epstein-Barr virus (EBV), enterovirus, Coxiella burnetii and parvovirus B19 revealed subtype-specific relationships for EBV and enterovirus, the two most common infectious triggers of CFS/ME.


Zhang, L., Goudh, J., Christmas, D., Mattey, D., Richards, S., Main, J., Enlander, D., Honeybourne, D., Ayres, J., Nutt, D. J., and Kerr, J. (2009). Microbial infections in eight genomic subtypes of chronic fatigue syndrome / myalgic encephalomyelitis (cfs/me). pages jcp.2009.072561+. http://www.citeulike.org/user/HEIRS/article/6306231