GSK-3b is required for hyperdopamine and d2 receptor-mediated inhibition of synaptic nmda receptor function in the rat prefrontal cortex.

Summary: This study suggests that GSK-3beta is required for the hyperdopamine/D(2) receptor-mediated inhibition of NMDA receptors in the prefrontal neurons and these actions may underlie D(2) receptor-mediated psychostimulant effects and hyperdopamine-dependent behaviors in the brain.Li, Y.-C. C., Xi, D., Roman, J., Huang, Y.-Q. Q., and Gao, W.-J. J. (2009). Activation of glycogen synthase kinase-3 beta is required for hyperdopamine and d2 receptor-mediated inhibition of synaptic nmda receptor function in the rat prefrontal cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience, 29(49):15551-15563. http://www.citeulike.org/user/HEIRS/article/6347607#