Paraoxonase 2 is downregulated by the pseudomonas aeruginosa quorum sensing signal n-(3-oxododecanoyl)-l-homoserine lactone and attenuates oxidative stress induced by pyocyanin

Background: Pseudomonas aeruginosa is a gram-negative pathogen that infects humans and other animals and is known to cause sepsis and generalized inflammation. (Wipedia)


Horke, S., Witte, I., Altenhöfer, S., Wilgenbus, P., Goldeck, M., Förstermann, U., Xiao, J., Kramer, G. L., Haines, D. C., Chowdhary, P. K., Haley, R. W., and Teiber, J. F. (2009). Paraoxonase 2 is downregulated by the pseudomonas aeruginosa quorum sensing signal n-(3-oxododecanoyl)-l-homoserine lactone and attenuates oxidative stress induced by pyocyanin. Biochemical Journal.