GST null genotype and antioxidants: Risk indicators for oral pre-cancer and cancer

Although the definitive cause of cancer is, as yet, unestablished, various risk factors such as genetic susceptibility, tobacco and alcohol consumption have been identified. It is well known that smokers and quid chewers do not necessarily develop cancer or precancerous states while the same can be found in individuals who are nonsmokers and quid chewers. Therefore, the possibility of genetic susceptibility or predisposition and alteration of the genes due to presence of carcinogens plays an important role in the development of these states... Click to read more.