Tuesday, November 30, 2010

The aryl hydrocarbon receptor (AHR), a novel regul... [Pigment Cell Melanoma Res. 2010] - PubMed result

The aryl hydrocarbon receptor (AHR), a novel regul... [Pigment Cell Melanoma Res. 2010] - PubMed result: "The aryl hydrocarbon receptor (AHR), a novel regulator of human melanogenesis."

Monday, November 29, 2010

Nrf2 Deficiency Influences Susceptibility to Stero... [Biochem Biophys Res Commun. 2010] - PubMed result

Nrf2 Deficiency Influences Susceptibility to Stero... [Biochem Biophys Res Commun. 2010] - PubMed result: "Nrf2 Deficiency Influences Susceptibility to Steroid Resistance via HDAC2 reduction"

Aging Reversed in Mice - ABC News

"Scientists have turned back the clock in mice they engineered to age faster than normal, an advance they suggest is the first time aging in mice has been reversed"

Read more: Aging Reversed in Mice - ABC News:

Sunday, November 28, 2010

Growth-Factor Gel Shows Promise As Hearing-Loss Treatment

"A new treatment has been developed for sudden sensorineural hearing loss (SSHL), a condition that causes deafness in 40,000 Americans each year, usually in early middle-age."

Read more: Growth-Factor Gel Shows Promise As Hearing-Loss Treatment:

Friday, November 26, 2010

HIF-2alpha, but not HIF-1alpha, promotes iron abso... [J Clin Invest. 2009] - PubMed result

HIF-2alpha, but not HIF-1alpha, promotes iron abso... [J Clin Invest. 2009] - PubMed result: "whereas HIF-2alpha played a crucial role in maintaining iron balance in the organism by directly regulating the transcription of the gene encoding divalent metal transporter 1 (DMT1), the principal intestinal iron transporter"

Hypoxia-inducible factor 2α regulates macrophage function in mouse models of acute and tumor inflammation

Hypoxia-inducible factor 2α regulates macrophage function in mouse models of acute and tumor inflammation: "HIF-2α (but not HIF-1α) directly activates the expression of Oct4, a critical transcription factor regulating stem cell maintenance (28), as well as the red blood cell cytokine erythropoietin (29)."

The Journal of clinical investigation, Vol. 120, No. 8. (2 August 2010), pp. 2699-2714.
http://www.citeulike.org/user/HEIRS/article/8311046

PGC-1alpha regulates a HIF2alpha-dependent switch in skeletal muscle fiber types.

"HIF2α acts downstream of PGC-1α as a key regulator of a muscle fiber-type program and the adaptive response to exercise."

Proceedings of the National Academy of Sciences of the United States of America (24 November 2010) http://www.citeulike.org/user/HEIRS/article/8311034

Health and Environmental Illness Research Blog: PGC-1a , Cold, MCK, Myogenesis and Nrf2 and Environmental Illness?!