Background: Recent studies suggest endotoxin may be a pathway to chronic fatigue syndrome and the associated inflammtory processes associated with it may contribute to a number of other acute, chronic and environmental diseases as well.
Title: Hypersensitivity of ahr-deficient mice to lps-induced septic shock.
Summary: This study suggests that absence of AhR expression results in increased expression of Il-1b and are hypersensitive to shock after exposure to LPS endotoxin.
Citation: Sekine, H., Mimura, J., Oshima, M., Okawa, H., Kanno, J., Igarashi, K., Gonzalez, F. J., Ikuta, T., Kawajiri, K., and Fujii-Kuriyama, Y. (2009). Hypersensitivity of ahr-deficient mice to lps-induced septic shock. Molecular and cellular biology. http://www.citeulike.org/user/HEIRS/article/5971045
